Peg Dmg
Peg Derivative Product
PEG or polyglycerin attached phospholipids (PEG phospholipid) are available for long circulating liposome formulations. Activated functional group attached phospholipids either PEG end or non PEG end are also available for immunoliposome or targeting use liposome. May 20, 2005 The PEG–S-DAGs possess hydrophobic domains of varying size, with two alkyl chains, either 14 (PEG–S-DMG), 16 (PEG–S-DPG) or 18 (PEG–S-DSG) carbon units in length. These are connected via a succinic acid linker to a PEG with a molecular weight of approximately 2000 Da. We provide evidence for the mode of action of PEG–lipids using an.
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The zeta potentials of adriamycin-encapsulating liposomes containing 1-(monomethoxy polyethyl-eneglycol)-2,3-dimyristoylglycerol (PEG-DMG) were measured in an isotonic solution of 10mM lactate buffer (pH 4.0) with sodium chloride and sucrose. The negativity of the zeta potentials of adriamycin-encapsulating liposomes containing PEG-DMG decreased with increases in NaCl concentration more steeply than that of adriamycin-encapsulating liposomes without PEG coating. From this observation, the electrical potential distributions near the membrane surfaces were shown to be different between adriamycin-encapsulating liposomes with and without PEG coating. Based on these zeta potential data, the thickness of the fixed aqueous layer around PEG-DMG-containing adriamycin liposomes was determined from the slope of In zeta potential versus Debye-Hiickel parameter plot. As a result, a correlation was indicated to exist between the circulation time of liposomes and the thickness of the aqueous layer around the liposomes.
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Peg Mgf 2mg
As carriers for delivery of therapeutic molecules. DMG -PEG GM-020 is a commercial available pegylated lipid with the average molecular weight of 2468 Da, and gaining worldwide interest as a drug delivery system polymer molecule due to its functional group which helps it fuse with the drug. Estasol® DMG is one of the many chemicals products available from Chemoxy’s speciality product range it is used for a variety of applications. Visit Chemoxy’s news page for information about the company and the broader chemical industry.